This work was supported by the National Research, Development, and Innovation Office of Hungary (NKFIA; NVKP_16-1-2016-0017-National Heart Program and K134939 to Dr. Radovits); the New National Excellence Program (ÚNKP-20-3-II-SE-54, ÚNKP-20-4-II-SE-20); the Artificial Intelligence National Laboratory Program; and the Thematic Excellence Program (2020-4.1.1.-TKP2020) of the Ministry for Innovation and Technology in Hungary, within the framework of the Therapeutic Development and Bioimaging programs of the Semmelweis University. Dr. Kovács was supported by the János Bolyai Research Scholarship of the Hungarian Academy of Sciences. All animal experiments complied with the Guide for the Care and Use of Laboratory Animals (provided by the US National Institutes of Health) and European Union Directive 2010/63/EU. The study protocol was approved by the Ethical Committee for Animal Experimentation, Semmelweis University, Budapest (approval PEI/001/2374-4/2015). All animals received humane care. The protocol of the human investigations conforms with the principles outlined in the Declaration of Helsinki and was approved by the Regional and Institutional Committee of Science and Research Ethics (approval 2016/175). All study participants provided written informed consent prior to enrollment. Dr. Sengupta is an advisor to Ultromics, Kencor Health and RCE Technologies. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. †Drs. Radovits and Kovács contributed equally to this paper.
